IHC of TAG-72 on an FFPE Breast Carcinoma Tissue
| Intended Use | For In Vitro Diagnostic Use | |||||||||||||||||||||||||||||||||||
| Summary and Explanation | Tumor-associated glycoprotein (TAG-72) has been shown to be expressed in a wide variety of epithelial malignant tissues. TAG-72 antigen is a high molecular glycoprotein found on the surface of many cancer cells, including breast, colon and pancreatic cells. It is present in human Adenocarcinomas and in lesser amounts, non-neoplastic tissues. The majority of human Adenocarcinomas including Colorectal, Pancreatic, Gastric, Ovarian, Endometrial, Mammary, and Non-Small Cell Lung Cancer display some cell populations that are positive for TAG-72. TAG-72 has also been found to be useful for the distinction between Mesothelioma and Adenocarcinoma; however, false positive reactions can occur so results must be interpreted with the utmost caution. | |||||||||||||||||||||||||||||||||||
| Antibody Type | Mouse Monoclonal | Clone | BSB-21 | |||||||||||||||||||||||||||||||||
| Isotype | IgG1/K | Reactivity | Paraffin, Frozen | |||||||||||||||||||||||||||||||||
| Localization | Cytoplasmic | Control | Breast Carcinoma | |||||||||||||||||||||||||||||||||
| Presentation | TAG-72 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative. | |||||||||||||||||||||||||||||||||||
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| Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product. | ||||||||||||||||||||||||||||||||||||
