IHC of PSP94 / MSMB on an FFPE Prostate Tissue
| Intended Use | For In Vitro Diagnostic Use | |||||||||||||||||||||||||||||||||||
| Summary and Explanation | Beta-microseminoprotein (MSMB) also called prostate secretory protein of 94 amino acids (PSP94), is one of the three predominant proteins secreted by the prostate gland and found in human seminal fluid along with prostate-specfic antigen and prostatic specific acid phosphatase. Using exogenous MSMB, in vitro and in vivo studies indicate that MSMB may have several anti-tumor effects on prostate tumor cells. MSMB expression is high in normal prostate epithelial cells, but is decreased in prostate cancer cells. Studies have shown that MSMB is a strong independent factor indicating favorable outcome after radical prostatectomy for localized prostate cancer. | |||||||||||||||||||||||||||||||||||
| Antibody Type | Rabbit Monoclonal | Clone | EP203 | |||||||||||||||||||||||||||||||||
| Isotype | IgG | Reactivity | Paraffin, Frozen | |||||||||||||||||||||||||||||||||
| Localization | Cytoplasmic | Control | Prostate, Prostatic Adenocarcinoma | |||||||||||||||||||||||||||||||||
| Presentation | PSP94/MSMB is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative. | |||||||||||||||||||||||||||||||||||
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| Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product. | ||||||||||||||||||||||||||||||||||||
