IHC of Progesterone Receptor on an FFPE Breast Carcinoma Tissue
| Intended Use | For Analyte Specific Reagent. | |||||||||||||||||||||||||||||||||||
| Summary and Explanation | The progesterone receptor (PR) also known as NR3C3 (nuclear receptor subfamily 3, group C, member 3), is an intracellular steroid receptor that specifically binds progesterone. PR is encoded by a single gene PGR residing on chromosome 11q22; it has two main forms, A and B, which differ in their molecular weight. Like all steroid receptors, the progesterone receptor has an amino and a carboxyl terminal, and between them the regulatory domain, a DNA binding domain, the hinge section, and the hormone binding domain. | |||||||||||||||||||||||||||||||||||
| Antibody Type | Rabbitt Monoclonal | Clone | EP2 | |||||||||||||||||||||||||||||||||
| Isotype | IgG | Reactivity | Paraffin, Frozen | |||||||||||||||||||||||||||||||||
| Localization | Nuclear | Control | Breast, Myometrium, Cervix, Fallopian Tube, Breast Carcinoma | |||||||||||||||||||||||||||||||||
| Presentation | Progesterone Receptor is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative. | |||||||||||||||||||||||||||||||||||
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| Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product. | ||||||||||||||||||||||||||||||||||||
