IHC of p40 on an FFPE Prostate Tissue
| Intended Use | For In Vitro Diagnostic Use | |||||||||||||||||||||||||||||||||||
| Summary and Explanation | p40 is an antibody that recognizes ΔNp63-a p63 isoform and it is highly specific for squamous/ basal cells. It may be a valuable marker in detecting Squamous Cell Carcinoma where p63 is currently used. It recognizes the shortest variant of p53. p40 is superior in specificity to p63 because it does not label lung adenocarinomas like p63 does, which eliminates the potential of misinterpreting a positive adenocarcinoma as a squamous cell carcinoma. | |||||||||||||||||||||||||||||||||||
| Antibody Type | Rabbit Monoclonal | Clone | ZR8 | |||||||||||||||||||||||||||||||||
| Isotype | IgG | Reactivity | Paraffin, Frozen | |||||||||||||||||||||||||||||||||
| Localization | Nuclear | Control | Normal Prostate, Breast, Skin | |||||||||||||||||||||||||||||||||
| Presentation | p40 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative. | |||||||||||||||||||||||||||||||||||
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| Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product. | ||||||||||||||||||||||||||||||||||||
