IHC of Hepatocyte Specific Antigen on an FFPE Liver Tissue
| Intended Use | For In Vitro Diagnostic Use | |||||||||||||||||||||||||||||||||||
| Summary and Explanation | Hepatocyte Specific Antigen (HSA or Hep Par 1) has been demonstrated consistently in the vast majority of Hepatocellular Carcinomas. Studies have shown the utility of HSA in the differential diagnosis of Hepatocellular Carcinoma, Cholangiocarcinoma and Hepatoblastomas. HSA recognizes both benign and malignant liver derived tissues including such tumors as Hepatoblastoma, Hepatocellular Carcinoma, and Hepatic Adenoma. It recognizes both normal adult and fetal liver tissue. The typical pattern is a granular cytoplasmic staining. This antibody is useful in differentiating Hepatocellular Carcinomas with adenoid features from Adenocarcinomas, either primary in the liver or metastatic lesions to the liver. In recognizing Hepatoblastoma, it is useful in differentiating this entity from other small round cell tumors. | |||||||||||||||||||||||||||||||||||
| Antibody Type | Mouse Monoclonal | Clone | OCH1E5 | |||||||||||||||||||||||||||||||||
| Isotype | IgG1/K | Reactivity | Paraffin, Frozen | |||||||||||||||||||||||||||||||||
| Localization | Cytoplasmic | Control | Liver, Liver Carcinoma | |||||||||||||||||||||||||||||||||
| Presentation | Anti-Hepatocyte Specific Antigen is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative. | |||||||||||||||||||||||||||||||||||
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| Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product. | ||||||||||||||||||||||||||||||||||||
