IHC of Hemaglobin A on an FFPE Placenta Tissue
| Intended Use | For In Vitro Diagnostic Use | |||||||||||||||||||||||||||||||||||
| Summary and Explanation | Hemoglobin alpha chain belongs to the globin family and is involved in oxygen transport from the lung to various peripheral tissues. It is a heterotetramer of two alpha chains and two beta chains in adult hemoglobin A (HbA); two alpha chains and two delta chains in adult hemoglobin A2 (HbA2). Hemoglobin alpha chain is expressed in red blood cells, and defects in HBA1/HBA2 can lead to alpha thalassemia, the most common of monogenic diseases. Hemoglobin alpha chain is a useful marker for erythroid cells. An antibody to Hemoglobin alpha has been used for the identification of erythroid cells in myeloproliferative disease. | |||||||||||||||||||||||||||||||||||
| Antibody Type | Rabbit Monoclonal | Clone | EP124 | |||||||||||||||||||||||||||||||||
| Isotype | IgG | Reactivity | Paraffin, Frozen | |||||||||||||||||||||||||||||||||
| Localization | Cytoplasmic | Control | Spleen, Bone Marrow, Placenta | |||||||||||||||||||||||||||||||||
| Presentation | Hemoglobin A is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative. | |||||||||||||||||||||||||||||||||||
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| Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product. | ||||||||||||||||||||||||||||||||||||
