IHC of Estrogen Receptor on an FFPE Breast Carcinoma Tissue
| Intended Use | Analyte Specific Reagent: analytical and performance characteristics are not established.* The ER alpha antibody, clone EP1, has been manufactured using Epitomics RabMab® technology covered under Patent No.’s 5,675,063 and 7,402,409. | |||||||||||||||||||||||||||||||||||
| Summary and Explanation | Estrogen receptor alpha (ER) is a nuclear receptor for estrogens such as estradiol (the main endogenous human estrogen). The two different estrogen receptor proteins produced from the ESR1 and ESR2 genes are usually called the alpha and beta receptors.This ER antibody recognizes a protein of 67 kDa, which is identified as estrogen receptor (ER) alpha. | |||||||||||||||||||||||||||||||||||
| Antibody Type | Rabbit Monoclonal | Clone | EP1 | |||||||||||||||||||||||||||||||||
| Isotype | IgG | Reactivity | Paraffin, Frozen | |||||||||||||||||||||||||||||||||
| Localization | Nuclear | Control | Breast, Myometrium, Cervix, Fallopian Tube, Breast Carcinoma | |||||||||||||||||||||||||||||||||
| Presentation | Estrogen receptor clone EP1 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative. | |||||||||||||||||||||||||||||||||||
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| Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product. | ||||||||||||||||||||||||||||||||||||
