IHC of Cytokeratin 5 on an FFPE Mesothelioma Tissue
| Intended Use | For In Vitro Diagnostic Use | |||||||||||||||||||||||||||||||||||
| Summary and Explanation | Cytokeratin 5 is a type II cytokeratin found in squamous cell epithelium, myoepithelial cells of the breast and the basal cells of the prostate. Both Cytokeratin 5 and its corresponding partner, Cytokeratin 14, are essential for formation of 8-nm filaments. Cytokeratin 5 is expressed in most Epithelial Mesotheliomas but not by most Pulmonary Adenocarcinomas and can be used to differentiate between the two. | |||||||||||||||||||||||||||||||||||
| Antibody Type | Rabbit Monoclonal | Clone | EP24 | |||||||||||||||||||||||||||||||||
| Isotype | IgG | Reactivity | Paraffin, Frozen | |||||||||||||||||||||||||||||||||
| Localization | Cytoplasmic | Control | Prostate, Breast, Placenta, Skin, Mesothelioma | |||||||||||||||||||||||||||||||||
| Presentation | CK5 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative. | |||||||||||||||||||||||||||||||||||
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| Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product. | ||||||||||||||||||||||||||||||||||||
