IHC of Cytokeratin 18 on an FFPE Colon Tissue
| Intended Use | For In Vitro Diagnostic Use | |||||||||||||||||||||||||||||||||||
| Summary and Explanation | Cytokeratin 18 is a type I cytokeratin and is typically partnered with Cytokeratin 8. They are expressed in simple and glandular and transitional epithelial cells but not in stratified epithelial cells. Cytokeratin 18 antibody stains positively in Adenocarcinomas originating from simple and glandular epithelium, and also in poorly differentiated tumor cells of Squamous Carcinoma. | |||||||||||||||||||||||||||||||||||
| Antibody Type | Rabbit Monoclonal | Clone | EP30 | |||||||||||||||||||||||||||||||||
| Isotype | IgG | Reactivity | Paraffin, Frozen | |||||||||||||||||||||||||||||||||
| Localization | Cytoplasmic | Control | Liver, Kidney, Breast, Breast Cancer, GI, Prostate, Fallopian Tube | |||||||||||||||||||||||||||||||||
| Presentation | CK18 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative. | |||||||||||||||||||||||||||||||||||
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| Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product. | ||||||||||||||||||||||||||||||||||||
