IHC of CD30 on an FFPE Hodgkin’s Lymphoma Tissue
| Intended Use | For In Vitro Diagnostic Use | |||||||||||||||||||||||||||||||||||
| Summary and Explanation | CD30 is a transmembrane cytokine receptor belonging to the tumor necrosis factor (TNF) receptor super- family. Mature CD30 has a molecular mass of 120 kDa and is derived from a 90 kDa precursor protein. CD30 antibody detects an epitope which is expressed by Reed-Sternberg cells in Hodgkin’s Disease, the majority of Anaplastic Large-cell Lymphomas, and in Embryonal Carcinomas and Seminomas. This antibody also stains plasma cells intensely in paraffin-embedded tissue. | |||||||||||||||||||||||||||||||||||
| Antibody Type | Mouse Monoclonal | Clone | Ber-H2 | |||||||||||||||||||||||||||||||||
| Isotype | IgG1/K | Reactivity | Paraffin, Frozen | |||||||||||||||||||||||||||||||||
| Localization | Membranous | Control | Tonsil, Lymph node, Hodgkin’s Lymphoma | |||||||||||||||||||||||||||||||||
| Presentation | CD30 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH 7.5, containing BSA and sodium azide as a preservative. | |||||||||||||||||||||||||||||||||||
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| Note: For concentrated antibodies, please centrifuge prior to use to ensure recovery of all product. | ||||||||||||||||||||||||||||||||||||
